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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP153
All Species:
17.27
Human Site:
Y427
Identified Species:
38
UniProt:
P49790
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49790
NP_005115.2
1475
153938
Y427
Q
R
E
S
G
F
S
Y
P
N
F
S
L
P
A
Chimpanzee
Pan troglodytes
XP_001170682
1475
154026
Y427
Q
R
E
S
G
F
S
Y
P
N
F
S
L
P
A
Rhesus Macaque
Macaca mulatta
XP_001096101
1474
153680
Y427
Q
R
E
S
G
F
S
Y
P
N
F
S
L
P
A
Dog
Lupus familis
XP_535898
1478
153685
Y428
E
Q
E
S
G
F
S
Y
P
N
F
S
M
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P49791
1468
152805
N428
E
S
G
F
S
Y
P
N
F
S
I
P
A
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508163
1644
167929
Y576
Q
H
E
S
N
F
S
Y
P
D
I
S
T
P
A
Chicken
Gallus gallus
XP_418937
1473
153350
K429
K
H
K
E
M
K
E
K
S
L
P
E
E
Q
R
Frog
Xenopus laevis
NP_001082284
1605
164952
P440
S
Y
P
K
F
S
T
P
A
S
N
G
L
S
S
Zebra Danio
Brachydanio rerio
XP_700317
1436
146282
R401
T
S
R
E
T
P
V
R
Q
S
P
P
I
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793520
1708
174739
S469
Y
G
A
P
I
T
S
S
T
P
A
E
G
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14907
823
86497
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.2
86.8
N.A.
N.A.
81.9
N.A.
62.8
64.5
43.7
43.5
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
99.4
98.3
91.7
N.A.
N.A.
88.9
N.A.
72.2
75.6
58.5
57.7
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
100
100
73.3
N.A.
N.A.
0
N.A.
66.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
N.A.
20
N.A.
73.3
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
0
10
0
10
10
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
19
0
46
19
0
0
10
0
0
0
0
19
10
0
10
% E
% Phe:
0
0
0
10
10
46
0
0
10
0
37
0
0
0
0
% F
% Gly:
0
10
10
0
37
0
0
0
0
0
0
10
10
0
0
% G
% His:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
19
0
10
0
0
% I
% Lys:
10
0
10
10
0
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
37
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
37
10
0
0
0
10
% N
% Pro:
0
0
10
10
0
10
10
10
46
10
19
19
0
46
0
% P
% Gln:
37
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
28
10
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
10
19
0
46
10
10
55
10
10
28
0
46
0
28
10
% S
% Thr:
10
0
0
0
10
10
10
0
10
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
10
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _